IgBert

Maintained By
Exscientia

IgBert

PropertyValue
Parameter Count420M
Model TypeBERT-based Transformer
LicenseMIT
PaperLarge scale paired antibody language models
Tensor TypeF32

What is IgBert?

IgBert is a sophisticated protein language model specifically designed for antibody sequence analysis. Developed by Exscientia, it represents a significant advancement in computational biology, utilizing a masked language modeling (MLM) objective and being fine-tuned on paired antibody sequences from the Observed Antibody Space.

Implementation Details

The model employs a BERT architecture optimized for processing protein sequences, particularly antibody pairs. It handles both heavy and light chain sequences, utilizing special tokens ([CLS], [SEP], [PAD]) for proper sequence structuring and processing.

  • Specialized tokenization system for protein sequences
  • Built-in support for paired sequence processing
  • Efficient embedding generation for both residue and sequence-level analysis
  • Flexible pooling options for downstream tasks

Core Capabilities

  • Processing paired antibody sequences
  • Generating meaningful protein embeddings
  • Supporting both sequence-level and residue-level analysis
  • Handling variable-length sequences through intelligent padding

Frequently Asked Questions

Q: What makes this model unique?

IgBert stands out for its specialized focus on paired antibody sequences and its large-scale architecture with 420M parameters, making it particularly effective for antibody-specific tasks and protein language modeling.

Q: What are the recommended use cases?

The model is ideal for antibody sequence analysis, protein structure prediction, and general protein language modeling tasks. It's particularly useful when working with paired heavy and light chain antibody sequences.

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